Hormonal Weight Gain

What Is Hormonal Weight Gain?

Weight gain associated with underlying hormonal imbalances. For men, hormonal weight gain can be caused by high stress or cortisol levels in the body. The heightened levels of cortisol may make the body go into survival mode and induce the production of fat cells which will cause a declining metabolism to store food for later use. For women, a specific estrogen hormone called estradiol decreases at menopause helps regulate metabolism and body weight. The lower the levels of estradiol may cause weight gain. Throughout a woman’s life, they may notice weight gain around their hips and thighs.

What Are The Causes Of Hormonal Weight Gain?

Hormonal weight gain can be caused by the following conditions or issues:

  • Thyroid hormone deficiency
  • Estrogen dominance
  • Androgen imbalance
  • Insulin resistance
  • Metabolic syndrome
  • PCOS
  • Growth hormone deficiency
  • Cortisol excess
  • Leptin resistance
  • Prolactin excess
  • Pituitary insufficiency

What Are The Signs And Symptoms Of Hormonal Weight Gain?

Any or none of these may be seen with Hormonal Weight Gain:

  • Thyroid goiter
  • Fatigue
  • Proximal muscle weakness
  • Moon faces
  • Central obesity – increase in abdominal and visceral fat
  • Purple striae
  • Acne
  • Hirsutism
  • Amenorrhea or impotence
  • Headache
  • Visual disturbances
  • Galactorrhea

What Are The Risk Factors Of Hormonal Weight Gain?

Risk factors include:

  • Genetics
  • Sedentary lifestyle
  • Aging
  • Hypothalamic/pituitary tumors or surgeries

How Is Hormonal Weight Gain Diagnosed?

An evaluation with an endocrinologist can help determine if a hormonal condition is the underlying cause of weight gain. Declining estrogen, adrenal disorders, hormonal resistance, thyroid imbalance, and several other hormonal imbalances can lead to weight gain. Laboratory tests give endocrinologists insight to hormonal imbalances when combined with your symptoms and presentation, but it doesn’t always tell the whole story. Blood and urine results can be influenced by many things. For this reason, we suggest special evaluations to see how metabolic information relates to the lab data.

What Are The Possible Treatments For Hormonal Weight Gain?

  • Dietary and lifestyle modifications, including but not limited to exercise and stress reduction
  • Thyroid hormone replacement
  • Testosterone replacement
  • OCPs
  • Other medications that target hormone excess or resistance to normalize levels
  • Medications to target appetite management and modulate insulin levels
  • Surgery (to remove a tumor that may be causing excess hormones to be produced)

Are There Preventative Steps Or Measures To Avoid Hormonal Weight Gain?

Seeking early evaluation with an endocrinologist so the appropriate interventions can be started sooner will help with minimizing and possibly reversing hormonal weight gain. Additionally, improving dietary choices, increasing physical activity, getting more sleep, managing stress levels effectively, quitting smoking, and limiting alcohol are all ways to decrease and avoid hormonal weight gain.

What Are The Risks If Hormonal Weight Gain Is Left Untreated?

Increased risk for development of Type 2 Diabetes, infertility, mood disturbances, hypertension, high cholesterol, heart disease (heart attacks), stroke, sleep apnea, asthma and cancer. Hormonal weight gain can also shorten your lifespan.

Are There Other Related Conditions To Hormonal Weight Gain?

Key Takeaways About Hormonal Weight Gain

  1. Hormonal weight gain is potentially reversible or treatable if the underlying cause is addressed and treated with the guidance of an endocrinologist.
  2. Hormonal weight gain can cause an increased risk for a multitude of other health conditions which can increase morbidity and mortality.
  3. Maintaining a healthy lifestyle through a balanced diet, regular physical activity, proper sleep, and stress modification can help with managing and reversing hormonal weight gain and decreasing the associated health risks that may result if it is not addressed.

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